Film & TV List | Role | Media |
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| 30 Rock (2006–2012) | Jack Donaghy (West Coast only) | TV Show |
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| To Rome with Love (2012) | John | Movie |
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| Hick (2011) | Beau | Movie |
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| It's Complicated (2009) | Jake | Movie |
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| Paul McCartney: Good Evening New York City (2009) | Narrator | TV Movie |
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| My Sister's Keeper (2009) | Campbell Alexander | Movie |
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| Madagascar: Escape 2 Africa (2008) | Makunga (voice) | Movie |
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| My Best Friend's Girl (2008) | Professor Turner | Movie |
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| Lymelife (2008) | Mickey Bartlett | Movie |
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| Brooklyn Rules (2007) | Caesar | Movie |
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| Suburban Girl (2007) | Archie Knox | Movie |
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| The Good Shepherd (2006) | Sam Murach | Movie |
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| Running with Scissors (2006) | Norman Burroughs | Movie |
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| The Departed (2006) | Ellerby | Movie |
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| Mini's First Time (2006) | Martin | Movie |
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| Great Performances (2006) | Luther Billis | TV Show |
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| Fun with Dick and Jane (2005) | Jack McCallister | Movie |
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| Will & Grace (2005) | Malcolm | TV Show |
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| The Simpsons (2005) | Dr. Caleb Thorn | TV Show |
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| Elizabethtown (2005) | Phil Devoss | Movie |
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| The Aviator (2004) | Juan Trippe | Movie |
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| Las Vegas (2004) | Jack Keller | TV Show |
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| The SpongeBob SquarePants Movie (2004) | Dennis (voice) | Movie |
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| Nip/Tuck (2004) | Dr. Barrett Moore | TV Show |
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| The Last Shot (2004) | Joe Devine | Movie |
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| The Fairly OddParents (2004) | Future Timmy | TV Show |
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| Along Came Polly (2004) | Stan Indursky | Movie |
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| Thomas & Friends: Best of Gordon (2004) | Narrator | Direct to Video |
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| Shortcut to Happiness (2004) | Jabez Stone | Movie |
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| Thomas the Tank Engine & Friends (1998–2003) | US Narrator
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Voices | TV Movie |
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| Dreams & Giants (2003) | Host | TV Movie |
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| Dr. Seuss' The Cat in the Hat (2003) | Quinn | Movie |
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| Second Nature (2003) | Paul Kane | TV Movie |
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| Walking with Cavemen (2003) | Narrator (USA version) (USA version) (USA version) (USA version) (USA version) | TV Movie |
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| The Cooler (2003) | Shelly Kaplow | Movie |
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| Path to War (2002) | Robert McNamara, Secretary of Defense | TV Movie |
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| Friends (2002) | Parker | TV Show |
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| The Royal Tenenbaums (2001) | Narrator (voice) | Movie |
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| Final Fantasy: The Spirits Within (2001) | Captain Gray Edwards (voice) | Movie |
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| Cats & Dogs (2001) | Butch (voice) | Movie |
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| Pearl Harbor (2001) | Lt. Col. James Doolittle | Movie |
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| Clerks (2000–2001) | Leonardo Leonardo | TV Show |
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| State and Main (2000) | Bob Barrenger | Movie |
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| Nuremberg (2000) | Justice Robert H. Jackson | TV Movie |
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| Thomas and the Magic Railroad (2000) | Mr. Conductor | Movie |
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| Outside Providence (1999) | Old Man Dunphy | Movie |
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| Thick as Thieves (1999) | Mackin | Movie |
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| The Confession (1999) | Roy Bleakie | Movie |
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| Mercury Rising (1998) | Nick Kudrow | Movie |
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| The Edge (1997) | Robert Green | Movie |
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| Ghosts of Mississippi (1996) | Bobby DeLaughter | Movie |
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| Heaven's Prisoners (1996) | Dave Robicheaux | Movie |
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| The Juror (1996) | Teacher | Movie |
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| A Streetcar Named Desire (1995) | Stanley Kowalski | TV Movie |
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| The Shadow (1994) | Lamont Cranston | Movie |
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| The Getaway (1994) | Carter 'Doc' McCoy | Movie |
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| Malice (1993) | Dr. Jed Hill | Movie |
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| The Larry Sanders Show (1993) | Alec Baldwin | TV Show |
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| Glengarry Glen Ross (1992) | Blake | Movie |
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| Prelude to a Kiss (1992) | Peter Hoskins | Movie |
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| The Marrying Man (1991) | Charley Pearl | Movie |
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| Alice (1990) | Ed | Movie |
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| Miami Blues (1990) | Frederick J. Frenger Jr. | Movie |
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| The Hunt for Red October (1990) | Jack Ryan | Movie |
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| Great Balls of Fire! (1989) | Jimmy Swaggart | Movie |
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| Talk Radio (1988) | Dan | Movie |
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| Working Girl (1988) | Mick Dugan | Movie |
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| Married to the Mob (1988) | 'Cucumber' Frank de Marco | Movie |
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| Beetlejuice (1988) | Adam Maitland | Movie |
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| She's Having a Baby (1988) | Davis McDonald | Movie |
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| Forever, Lulu (1987) | Buck | Movie |
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| The Alamo: Thirteen Days to Glory (1987) | Col. William Barrett Travis | TV Movie |
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| Dress Gray (1986) | Rysam 'Ry' Slaight | TV Movie |
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| Knots Landing (1984–1985) | Joshua Rush | TV Show |
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| Love on the Run (1985) | Sean Carpenter | TV Movie |
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| Hotel (1985) | Dennis Medford | TV Show |
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| Sweet Revenge (1984) | Maj. Alex Breen | TV Movie |
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| Cutter to Houston (1983) | Dr. Hal Wexler | TV Show |
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| The Doctors (1980–1982) | Billy Allison Aldrich | TV Show |
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