Film & TV List | Role | Media |
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| Cougar Town (2009–2012) | Jules Cobb | TV Show |
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| Web Therapy (2011) | Serena Duvall | TV Show |
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| Scream 4 (2011) | Gale Weathers-Riley | Movie |
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| Web Therapy (2009) | Serena DuVall | TV Show |
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| Scrubs (2001–2009) | Dr. Taylor Maddox | TV Show |
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| Bedtime Stories (2008) | Wendy | Movie |
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| Dirt (2007–2008) | Lucy Spiller | TV Show |
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| The Tripper (2006) | Cynthia | Movie |
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| Zoom (2006) | Marsha Holloway | Movie |
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| Barnyard (2006) | Daisy the Cow (voice) | Movie |
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| Friends (1994–2004) | Monica Geller-Bing | TV Show |
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| November (2004) | Sophie Jacobs | Movie |
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| Get Well Soon (2001) | Lily Charles | Movie |
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| The Shrink Is In (2001) | Samantha Crumb | Movie |
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| 3000 Miles to Graceland (2001) | Cybil Waingrow | Movie |
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| Scream 3 (2000) | Gale Weathers | Movie |
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| The Runner (1999) | Karina | Movie |
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| Happily Ever After: Fairy Tales for Every Child (1999) | Emerald Salt Pork | TV Show |
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| Scream 2 (1997) | Gale Weathers | Movie |
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| Commandments (1997) | Rachel Luce | Movie |
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| Scream (1996) | Gale Weathers | Movie |
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| The Larry Sanders Show (1995) | Courteney Cox | TV Show |
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| Sketch Artist II: Hands That See (1995) | Emmy | TV Movie |
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| Seinfeld (1994) | Meryl | TV Show |
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| Ace Ventura: Pet Detective (1994) | Melissa Robinson | Movie |
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| The Trouble with Larry (1993) | Gabriella Easden | TV Show |
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| The Opposite Sex and How to Live with Them (1992) | Carrie Davenport | Movie |
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| Dream On (1992) | Alisha | TV Show |
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| Battling for Baby (1992) | Katherine | TV Movie |
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| Morton & Hayes (1991) | Princess Lucy | TV Show |
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| Blue Desert (1991) | Lisa Roberts | Movie |
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| Shaking the Tree (1990) | Kathleen | Movie |
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| Mr. Destiny (1990) | Jewel Jagger | Movie |
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| Curiosity Kills (1990) | Gwen | TV Movie |
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| Till We Meet Again (1989) | Marie-Frederique 'Freddy' de Lancel
/
Marie-Frederique 'freddy' de Lancel | TV Movie |
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| Roxanne: The Prize Pulitzer (1989) | Jacquie Kimberly | TV Movie |
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| Family Ties (1987–1989) | Lauren Miller | TV Show |
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| I'll Be Home for Christmas (1988) | Nora Bundy | TV Movie |
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| Cocoon: The Return (1988) | Sara | Movie |
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| Misfits of Science (1985–1988) | Gloria Dinallo | TV Show |
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| If It's Tuesday, It Still Must Be Belgium (1987) | Hana Wyshocki | TV Movie |
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| Masters of the Universe (1987) | Julie Winston | Movie |
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| Down Twisted (1987) | Tarah | Movie |
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| Murder, She Wrote (1986) | Carol Bannister | TV Show |
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| Sylvan in Paradise (1986) | Lucy Apple | TV Movie |
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| The Love Boat (1986) | Carol | TV Show |
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| As the World Turns (1984) | Bunny | TV Show |
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Film & TV List | Role | Media |
 |
| The Late Late Show with Craig Ferguson (2011–2012) | Guest | TV Show |
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| Good Morning America (2012) | Guest | TV Show |
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| Late Show with David Letterman (1997–2011) | Herself
/
Herself - Guest | TV Show |
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| Entertainment Tonight (2003–2010) | Herself | TV Show |
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| Dancing with the Stars (2009) | Herself - Guest Appearance | TV Show |
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| The Tonight Show with Conan O'Brien (2009) | Herself | TV Show |
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| American Idol (2008) | Herself - Audience Member | TV Show |
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| The Tonight Show with Jay Leno (1994–2007) | Herself
/
Herself - From Las Vegas | TV Show |
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| The Oprah Winfrey Show (2003–2004) | Herself | TV Show |
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| The View (2003) | Herself | TV Show |
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| Late Night with Conan O'Brien (1997) | Herself | TV Show |
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| Saturday Night Live (1995) | Herself - Host | TV Show |
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