| cast |
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| Series Regulars | |||
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| Rachel Bilson | Rachel Bilson as Dr. Zoe Hart | Jaime King | Jaime King as Lemon Breeland |
| Scott Porter | Scott Porter as George Tucker | Wilson Bethel | Wilson Bethel as Wade Kinsella |
| Cress Williams | Cress Williams as Lavon Hayes | Tim Matheson | Tim Matheson as Dr. Brick Breeland |
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| Recurring & Guests | |||
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| Reginald VelJohnson | Reginald VelJohnson as Dash DeWitt | McKaley Miller | McKaley Miller as Rose Hattenbarger |
| Nadine Velazquez | Nadine Velazquez as Didi Ruano | Wes Brown | Wes Brown as Dr. Judson Lyons |