| cast |
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| Series Regulars | |||
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| Alex O'Loughlin | Alex O'Loughlin as Det. Steve McGarrett | Grace Park | Grace Park as Kono Kalakaua |
| Daniel Dae Kim | Daniel Dae Kim as Det. Chin Ho Kelly | Scott Caan | Scott Caan as Danny "Danno" Williams |
| Masi Oka | Masi Oka as Dr. Max Bergman | Will Yun Lee | Will Yun Lee as Sang Min |
| Taryn Manning | Taryn Manning as Mary Ann McGarrett | | |
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| Recurring & Guests | |||
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| Mark Dacascos | Mark Dacascos as Wo Fat | Larisa Oleynik | Larisa Oleynik as Jenna Kaye |
| Jean Smart | Jean Smart as Governor Pat Jameson | Terry O'Quinn | Terry O'Quinn as Lieutenant Commander Joe White |
| Lauren German | Lauren German as Officer Lori Weston | Michelle Borth | Michelle Borth as Catherine Rollins |