| cast |
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| Series Regulars | |||
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| Adam Rayner | Adam Rayner as Dr. Steve Shaw | Christina Moore | Christina Moore as Candy Sullivan |
| David Julian Hirsh | David Julian Hirsh as Ray Stein | Hannah Hodson | Hannah Hodson as Camille Hawthorne |
| Jada Pinkett Smith | Jada Pinkett Smith as Christina Hawthorne | James Morrison | James Morrison as John Morrissey |
| Marc Anthony | Marc Anthony as Detective Nick Renata | Michael Vartan | Michael Vartan as Dr. Tom Wakefield |
| Suleka Mathew | Suleka Mathew as Bobbie Jackson | Vanessa Lengies | Vanessa Lengies as Kelly Epson |
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| Recurring & Guests | |||
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| Abigail Spencer | Abigail Spencer as Dr. Erin Jameson | Aisha Hinds | Aisha Hinds as Isabel Walsh |
| Derek Luke | Derek Luke as Dr. Miles Bourdet | Dot Jones | Dot Jones as Dot |
| Noureen DeWulf | Noureen DeWulf as Judy Pasram | Sara Gilbert | Sara Gilbert as Malia Price |