| cast |
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| Series Regulars | |||
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| Gabriel Byrne | Gabriel Byrne as Dr. Paul Weston | | |
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| Recurring & Guests | |||
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| Alex Wolff | Alex Wolff as Max | Alison Pill | Alison Pill as April |
| Amy Ryan | Amy Ryan as Adele | Blair Underwood | Blair Underwood as Alex Prince |
| Dane DeHaan | Dane DeHaan as Jesse | Debra Winger | Debra Winger as Frances |
| Dianne Wiest | Dianne Wiest as Dr. Gina Toll | Embeth Davidtz | Embeth Davidtz as Amy |
| Hope Davis | Hope Davis as Mia | Irrfan Khan | Irrfan Khan as Sunil |
| Josh Charles | Josh Charles as Jake | Mae Whitman | Mae Whitman as Rosie Weston |
| Melissa George | Melissa George as Laura Hill | Mia Wasikowska | Mia Wasikowska as Sophie |
| Russell Hornsby | Russell Hornsby as Luke | Sherri Saum | Sherri Saum as Bess |