| cast |
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| Series Regulars | |||
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| Brendan Hines | Brendan Hines as Eli Loker | Kelli Williams | Kelli Williams as Dr. Gillian Foster |
| Mekhi Phifer | Mekhi Phifer as Ben Reynolds | Monica Raymund | Monica Raymund as Ria Torres |
| Tim Roth | Tim Roth as Dr. Cal Lightman | | |
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| Recurring & Guests | |||
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| Erika Christensen | Erika Christensen | James Marsters | James Marsters |
| Jennifer Beals | Jennifer Beals as Zoe Landau | Monique Gabriela Curnen | Monique Gabriela Curnen as Detective Sharon Wallowski |