Film & TV List | Role | Media |
 |
| Weeds (2005–2011) | Nancy Botwin | TV Show |
|
| Red (2010) | Sarah Ross | Movie |
|
| Howl (2010) | Gail Potter | Movie |
|
| Solitary Man (2009) | Jordon Karsch | Movie |
|
| The Spiderwick Chronicles (2008) | Helen Grace | Movie |
|
| The Assassination of Jesse James by the Coward Robert Ford (2007) | Zee James | Movie |
|
| The Robber Bride (2007) | Zenia Arden | TV Movie |
|
| The West Wing (2001–2006) | Amy Gardner | TV Show |
|
| Romance & Cigarettes (2005) | Constance | Movie |
|
| Vinegar Hill (2005) | Ellen Grier | TV Movie |
|
| Miracle Run (2004) | Corrine Morgan-Thomas | TV Movie |
|
| Saved! (2004) | Lillian | Movie |
|
| The Best Thief in the World (2004) | Sue Zaidman | Movie |
|
| Angels in America (2003) | Harper Pitt | TV Movie |
|
| Master Spy: The Robert Hanssen Story (2002) | Bonnie Hanssen | TV Movie |
|
| Red Dragon (2002) | Molly Graham | Movie |
|
| Pipe Dream (2002) | Toni Edelman | Movie |
|
| Cupid & Cate (2000) | Cate DeAngelo | TV Movie |
|
| The Five Senses (1999) | Rona | Movie |
|
| The Simple Life of Noah Dearborn (1999) | Dr. Valerie Crane | TV Movie |
|
| Let the Devil Wear Black (1999) | Julia Hirsch | Movie |
|
| Saint Maybe (1998) | Lucy Dean Bedloe | TV Movie |
|
| Legalese (1998) | Rica Martin | TV Movie |
|
| Goodbye Lover (1998) | Peggy Blane | Movie |
|
| Murder in Mind (1997) | Caroline Walker | Movie |
|
| The Maker (1997) | Officer Emily Peck | Movie |
|
| The Portrait of a Lady (1996) | Henrietta Stackpole | Movie |
|
| Sugartime (1995) | Phyllis McGuire | TV Movie |
|
| Reckless (1995) | Pooty | Movie |
|
| Boys on the Side (1995) | Robin | Movie |
|
| Bullets Over Broadway (1994) | Ellen | Movie |
|
| The Client (1994) | Dianne Sway | Movie |
|
| A Place for Annie (1994) | Linda | TV Movie |
|
| Mr. Wonderful (1993) | Rita | Movie |
|
| Naked in New York (1993) | Joanne White | Movie |
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| Fried Green Tomatoes (1991) | Ruth Jamison | Movie |
|
| Grand Canyon (1991) | Dee | Movie |
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| Longtime Companion (1989) | Lisa | Movie |
|
| Signs of Life (1989) | Charlotte | Movie |
|
| Too Young the Hero (1988) | Pearl Spencer | TV Movie |
|
| Ryan's Hope (1975) | n/a | TV Show |
|
Film & TV List | Role | Media |
|
| The Tonight Show with Jay Leno (2011) | Herself | TV Show |
|
| The Late Late Show with Craig Ferguson (2009–2011) | Herself
/
Herself - At 'Red' Premiere
/
Herself - Guest | TV Show |
|
| Chelsea Lately (2009) | Herself | TV Show |
|
| Entertainment Tonight (2009) | Herself | TV Show |
|
| Late Show with David Letterman (1995–2009) | Herself - Guest
/
Herself | TV Show |
|