Film & TV List | Role | Media |
 |
| The Good Wife (2010–2012) | Louis Canning | TV Show |
|
| Phineas and Ferb (2011) | Michael
/
Werewolf | TV Show |
|
| Curb Your Enthusiasm (2011) | Michael J. Fox | TV Show |
|
| Rescue Me (2009) | Dwight | TV Show |
|
| The Magic 7 (2009) | Marcel Maggot (voice) | TV Movie |
|
| Boston Legal (2006) | Daniel Post | TV Show |
|
| Stuart Little 3: Call of the Wild (2005) | Stuart Little (voice) | Direct to Video |
|
| Scrubs (2004) | Dr. Kevin Casey | TV Show |
|
| Clone High (2002) | Gandhi's Remaining Kidney | TV Show |
|
| Stuart Little 2 (2002) | Stuart Little (voice) | Movie |
|
| Interstate 60: Episodes of the Road (2002) | Mr. Baker | Movie |
|
| Spin City (1996–2001) | Mike Flaherty | TV Show |
|
| Atlantis: The Lost Empire (2001) | Milo James Thatch (voice) | Movie |
|
| Stuart Little (1999) | Stuart Little (voice) | Movie |
|
| Mars Attacks! (1996) | Jason Stone | Movie |
|
| The Frighteners (1996) | Frank Bannister | Movie |
|
| Homeward Bound 2: Lost in San Francisco (1996) | Chance (voice) | Movie |
|
| The American President (1995) | Lewis Rothschild | Movie |
|
| Blue in the Face (1995) | Pete Maloney | Movie |
|
| Coldblooded (1995) | Tim Alexander | Movie |
|
| Don't Drink the Water (1994) | Axel Magee | TV Movie |
|
| Greedy (1994) | Daniel | Movie |
|
| Where the Rivers Flow North (1993) | Clayton Farnsworth | Movie |
|
| For Love or Money (1993) | Doug Ireland | Movie |
|
| Life with Mikey (1993) | Michael Chapman | Movie |
|
| Homeward Bound: The Incredible Journey (1993) | Chance (voice) | Movie |
|
| Shelley Duvall's Bedtime Stories (1992) | Narrator (segment There's a Nightmare in My Closet) (segment There's a Nightmare in My Closet) (voice) | TV Show |
|
| Doc Hollywood (1991) | Dr. Benjamin Stone | Movie |
|
| Tales from the Crypt (1991) | Prosecutor | TV Show |
|
| The Hard Way (1991) | Nick Lang | Movie |
|
| Back to the Future Part III (1990) | Marty McFly | Movie |
|
| Back to the Future Part II (1989) | Marty McFly | Movie |
|
| Casualties of War (1989) | Eriksson | Movie |
|
| Family Ties (1982–1989) | Alex P. Keaton | TV Show |
|
| Mickey's 60th Birthday (1988) | Alex P. Keaton | TV Movie |
|
| Bright Lights, Big City (1988) | Jamie Conway | Movie |
|
| The Secret of My Succe$s (1987) | Brantley Foster | Movie |
|
| Light of Day (1987) | Joe Rasnick | Movie |
|
| David Letterman's 2nd Annual Holiday Film Festival (1986) | n/a (segment The Iceman Hummeth) | TV Movie |
|
| Family Ties Vacation (1985) | Alex P. Keaton | TV Movie |
|
| Teen Wolf (1985) | Scott Howard | Movie |
|
| Back to the Future (1985) | Marty McFly | Movie |
|
| Poison Ivy (1985) | Dennis Baxter | TV Movie |
|
| Night Court (1984) | Eddie Simms | TV Show |
|
| Don't Ask Me, Ask God (1984) | Future Son | TV Movie |
|
| High School U.S.A. (1983) | Jay-Jay Manners | TV Movie |
|
| The Love Boat (1983) | Jimmy Cowens | TV Show |
|
| Class of 1984 (1982) | Arthur | Movie |
|
| Teachers Only (1982) | Jeff | TV Show |
|
| Palmerstown, U.S.A. (1980–1981) | Willy-Joe Hall | TV Show |
|
| Leo and Me (1981) | Jamie | TV Show |
|
| Trapper John, M.D. (1981) | Elliot Schweitzer | TV Show |
|
| Trouble in High Timber Country (1980) | Thomas Elston | TV Movie |
|
| Here's Boomer (1980) | Jackie | TV Show |
|
| Family (1980) | Richard Topol | TV Show |
|
| Midnight Madness (1980) | Scott Larson | Movie |
|
| Lou Grant (1979) | Paul Stone | TV Show |
|
| Letters from Frank (1979) | Ricky | TV Movie |
|
| The Magic Lie (1977) | Nicky | TV Show |
|
| The Beachcombers (1973) | n/a | TV Show |
|
Film & TV List | Role | Media |
|
| Late Show with David Letterman (1993–2011) | Himself
/
Himself - Guest | TV Show |
|
| The Oprah Winfrey Show (2002–2011) | Himself | TV Show |
|
| Ace of Cakes (2011) | Himself | TV Show |
|
| Dancing with the Stars (2010) | Himself - Audience Member | TV Show |
|
| The Colbert Report (2010) | Himself | TV Show |
|
| Late Night with Jimmy Fallon (2010) | Himself | TV Show |
|
| Entertainment Tonight (1990–2010) | Himself | TV Show |
|
| The Daily Show with Jon Stewart (1997–2009) | Himself | TV Show |
|
| The Apprentice (2006) | Himself | TV Show |
|
| Late Night with Conan O'Brien (1998–2004) | Himself | TV Show |
|
| The Tonight Show with Jay Leno (1993–1998) | Himself
/
Himself - From New York | TV Show |
|
| Good Morning America (1994) | Himself | TV Show |
|
| Saturday Night Live (1991) | Dan Quayle | TV Show |
|