| cast |
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| Series Regulars | |||
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| Alimi Ballard | Alimi Ballard as David Sinclair | Aya Sumika | Aya Sumika as Liz Warner |
| David Krumholtz | David Krumholtz as Charlie Eppes | Diane Farr | Diane Farr as Megan Reeves |
| Dylan Bruno | Dylan Bruno as Colby Granger | Judd Hirsch | Judd Hirsch as Alan Eppes |
| Navi Rawat | Navi Rawat as Amita Ramanujan | Peter MacNicol | Peter MacNicol as Dr. Larry Fleinhardt |
| Rob Morrow | Rob Morrow as Don Eppes | Sophina Brown | Sophina Brown as Nikki Betancourt |
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| Recurring & Guests | |||
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| Lou Diamond Phillips | Lou Diamond Phillips as Agent Ian Edgerton | Wendell Pierce | Wendell Pierce as William Bradford |