| cast |
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| Series Regulars | |||
| |||
| Anna Deavere Smith | Anna Deavere Smith as Gloria Akalitus | Arjun Gupta | Arjun Gupta as Sam |
| Bobby Cannavale | Bobby Cannavale | Dominic Fumusa | Dominic Fumusa as Kevin Peyton |
| Edie Falco | Edie Falco as Jackie O'Hurley | Eve Best | Eve Best as Dr. Eleanor O'Hara |
| Haaz Slieman | Haaz Slieman as Mo-Mo | Mackenzie Aladjem | Mackenzie Aladjem as Fiona Peyto |
| Merritt Wever | Merritt Wever as Zoey Barkow | Paul Schulze | Paul Schulze as Eddie Walzer |
| Peter Facinelli | Peter Facinelli as Dr. Fitch Cooper | Stephen Wallem | Stephen Wallem as Thor |
| |||
| Recurring & Guests | |||
| |||
| Daisy Tahan | Daisy Tahan as Fiona Peyton | Jaimie Alexander | Jaimie Alexander as Tunie Peyton |