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Series Regulars
Wentworth MillerWentworth Miller
as Michael Scofield
Dominic PurcellDominic Purcell
as Lincoln Burrows
Amaury NolascoAmaury Nolasco
as Fernando Sucre
Robert KnepperRobert Knepper
as Theodore "T-Bag" Bagwell
Sarah Wayne CalliesSarah Wayne Callies
as Dr. Sara Tancredi
Wade WilliamsWade Williams
as Brad Bellick
William FichtnerWilliam Fichtner
as Alex Mahone
Paul AdelsteinPaul Adelstein
as Paul Kellerman
Marshall AllmanMarshall Allman
as LJ Burrows
Rockmond DunbarRockmond Dunbar
as Benjamin Miles "C-Note" Franklin
Jodi Lyn O'KeefeJodi Lyn O'Keefe
as Gretchan Morgan
Peter StormarePeter Stormare
as John Abruzzi
Stacy KeachStacy Keach
as Warden Henry Pope
Robin TunneyRobin Tunney
as Veronica Donovan
Michael RapaportMichael Rapaport
as Don Self
 
Recurring & Guests
Barbara Eve HarrisBarbara Eve Harris
as FBI Agent Felicia Lang
Patricia WettigPatricia Wettig
as Vice President Caroline Reynolds
Frank GrilloFrank Grillo
as Nick Savrinn
Christian StolteChristian Stolte
as Corrections Officer Keith Stolte
Lane GarrisonLane Garrison
as David "Tweener" Apolskis
Reggie LeeReggie Lee
as Bill Kim
Danay GarciaDanay Garcia
as Sofia Lugo
Chris VanceChris Vance
as James Whistler
Robert WisdomRobert Wisdom
as Lechero
Silas Weir MitchellSilas Weir Mitchell
as Charles "Haywire" Patoshik
Shannon LucioShannon Lucio
as Miriam Holtz
Laurence MasonLaurence Mason
as Sammy
John HeardJohn Heard
as Governor Frank Tancredi
Callie ThorneCallie Thorne
as Pam Mahone
Cress WilliamsCress Williams
as Wyatt
Camille GuatyCamille Guaty
as Maricruz Delgado
Stacy HaidukStacy Haiduk
as Lisa Tabak
Michelle ForbesMichelle Forbes
as Samantha Brinker
James Hiroyuki LiaoJames Hiroyuki Liao
as Roland Glenn
Tony DenisonTony Denison
as Aldo Burrows
Kim CoatesKim Coates
as Agent Richard Sullins
Raphael SbargeRaphael Sbarge
as Ralph Becker
Dylan MinnetteDylan Minnette
as Young Michael
Danielle CampbellDanielle Campbell
as Gracey Hollander
Jessalyn GilsigJessalyn Gilsig
as Lisa Rix
Graham McTavishGraham McTavish
as Ferguson
Anthony StarkeAnthony Starke
as Sebastian Balfour
Jeff PerryJeff Perry
as Terrence Steadman