| cast |
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| Series Regulars | |||
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| Mark Feuerstein | Mark Feuerstein as Dr. Hank Lawson | Paulo Costanzo | Paulo Costanzo as Evan R. Lawson |
| Jill Flint | Jill Flint as Jill Casey | Reshma Shetty | Reshma Shetty as Divya Katdare |
| Christine Ebersole | Christine Ebersole as Ms. Newberg | | |
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| Recurring & Guests | |||
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| Ezra Miller | Ezra Miller as Tucker Bryant | Campbell Scott | Campbell Scott as Boris Kuester von Jurgens-Ratenicz |
| Brooke D'Orsay | Brooke D'Orsay as Paige Collins | Henry Winkler | Henry Winkler as Eddie R. Lawson |
| Paola Turbay | Paola Turbay as Dr. Marissa Caseras | Anastasia Griffith | Anastasia Griffith as Dr. Emily Peck |
| Meredith Hagner | Meredith Hagner as Libby | Bob Gunton | Bob Gunton as General William Collins |
| Marcia Gay Harden | Marcia Gay Harden as Dr. Elizabeth Blair | Bruno Campos | Bruno Campos as Charlie Casey |
| Andrew McCarthy | Andrew McCarthy as Marshall Bryant | Kyle Howard | Kyle Howard as Dr. Paul Van Dyke |
| Tom Cavanagh | Tom Cavanagh as Jack O'Malley | JoAnna Garcia | JoAnna Garcia as Dr. Nina Greene |