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Cast of "Samantha Who?"
Cast of "Samantha Who?" - © ABC
8 PICTURES
Tim Russ as Frank on "Samantha Who?" Kevin Dunn as Howard on "Samantha Who?" Jennifer Esposito as Andrea on "Samantha Who?" Christina Applegate as Samantha on "Samantha Who?" Jean Smart as Regina on "Samantha Who?" Barry Watson as Todd on "Samantha Who?" Melissa McCarthy as Dena on "Samantha Who?" Samantha Who? Pictures
Christina Applegate returns to network television in ABC's "Samantha Who??,"  a comedy that offers a do-over in life.

What if you had the chance to start over, to do it all again? For Samantha Newly (Christina Applegate), this fantasy becomes a reality after a hit-and-run accident leaves her in an eight-day coma on "Samantha Who?" When she awakens in the hospital on "Samantha Who?," she is surrounded by family and friends. The only problem is that she has no idea who they are - or who she is. In medical terms, Sam has retrograde amnesia, which allows her to fully function in the world but leaves her with no personal memories. Most people would deem this disorder a curse. But Sam may come to call it a miracle.

As she sets out to rediscover herself on "Samantha Who?," Sam is forced to rely on the only people who can help her -- an eclectic bunch of friends and family. Although now strangers to Sam, it's not long before she begins to get an idea of who she was before the accident.

On "Samantha Who?" Regina (Jean Smart, "24," "Designing Women") and Howard (Kevin Dunn, "Transformers," "Dave") appear to be loving parents -- when they're not downplaying the fact that Sam hasn't spoken to them in two years. Her supposed best friend, Dena (Melissa McCarthy, "Gilmore Girls"), is sincerely supportive, until her real best friend, Andrea (Jennifer Esposito, "Crash," "Spin City"), exposes Dena as a fraud who hasn't seen or spoken to Sam since the seventh grade. Andrea is a party girl who seems to have Sam's best interests at heart. However in the midst of celebrating her return on "Samantha Who?," Andrea neglects to mention that Sam's an alcoholic, is having an affair with a married man, and has a tendency for all-around morally questionable behavior. Sam's only seemingly trustworthy acquaintance is boyfriend Todd (Barry Watson, "What About Brian," "7th Heaven"). But will that trust last when he discovers that she cheated on him?

ON "Samantha Who?" Sam quickly discovers she was a horrible person. Vain, selfish and potentially surrounded by far more enemies than friends. She makes a conscious decision on "Samantha Who?" to improve herself moving forward. She vows to make better choices, even though her instincts may not always steer her in the right direction. She begins with Frank (Tim Russ, "Live Free or Die Hard," "Star Trek: Voyager"), the doorman at Todd's apartment building. Sam never gave him the time of day before, but upon actually saying hello to him, she discovers an incredibly observant and unlikely confidant.

On "Samantha Who?" Sam will need to continue to piece together things from her past to guide her in discovering who she is... or was. After all, sometimes to get to the end of the story, the only place to start is the beginning.

"Samantha Who?" stars Christina Applegate as Samantha, Jennifer Esposito as Andrea, Kevin Dunn as Howard, Melissa McCarthy as Dena, Tim Russ as Frank with Barry Watson as Todd and Jean Smart as Regina.

"Samantha Who?" was created by Cecelia Ahern and Donald Todd. Todd and Peter Traugott serve as executive producers. "Samantha Who?," which is filmed in Los Angeles, is from ABC Studios.






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SAMANTHA WHO?: NEWS (13)


Cast of "Samantha Who?"2009 Emmy Award Nominations Announced"30 Rock" and "Mad Men" come out on top again this year for comedy and drama series with 22 and 16 nominations respectively, while "Grey Gardens" cultivates 17, "Into the West" rides into the sunset with 14, "Saturday Night Live" yucks it up for 13, and "Dancing with the Stars" waltzes away with 10. Read more...
"Desperate Housewives" CastDisney Partners with HuluAmong the ABC, ABC Family, and Disney Channel shows to become available for streaming soon: "Lost," "Grey's Anatomy," "Desperate Housewives," "Ugly Betty," "Samantha Who?," "Scrubs" and "Private Practice." Read more...
Kathy Griffin on "Kathy Griffin: My Life on the D-List"Kathy Griffin Hosts 'The A-List Awards' to Celebrate the Best in Food, Fashion, Beauty, Design and Pop CultureThe awards ceremony will take place at The Orpheum Theatre in Los Angeles on Sunday, April 5. Read more...
SEE ALL "SAMANTHA WHO?" NEWS (13)


 
 
 
 
SAMANTHA WHO?: TWEETS

Watching the stupid Samantha who ?
less than an hour ago
at the play with deven david and samantha!! i feeel like the loud black woman who gets killed in the theaters from scary movie one
4 hours ago
i might just change my facebook name to 'sam tirrell'. like, really. who calls me samantha?
5 hours ago
@rahhmazingx3 woahh dood. That's insane. We took samantha to Confucius and there was this guy who didn't know how to use chopsticks. Lmfao.
5 hours ago
RT @garyvee: Who Likes Samantha Brown from the travel channel? Watching episode 772 right now! Like right now! Really, right now!
7 hours ago
Who Likes Samantha Brown from the travel channel? (via @garyvee)
7 hours ago
RT @irabrooker: Samantha from 'Who's the Boss' sure is pretty. I only wish there was some means of learning her feelings on current tech
8 hours ago
I adore @1capplegate shes my favourite actress ! shes so funny in the sweetiest thing & samantha who ! Shes a pretty amazing girl :) <33 xox
8 hours ago
@garyvee Who doesn't like Samantha Brown from the travel channel?
8 hours ago
@garyvee My apologies Sr.... Samantha who?
8 hours ago
@garyvee who DOESN'T would be the better question :) Samantha is gorgeous and has a great personality. Love watching the show
8 hours ago
@garyvee. Moms. The answer to your question "Who likes Samantha Brown?" is moms.
8 hours ago
Who Likes Samantha Brown from the travel channel?
8 hours ago
"There's two kinds of guys. The ones who hold your hand and the ones that f**k you" I LOVE SAMANTHA JONES! hahaha
10 hours ago
FRI Free Smirnoff Event, Extreme Night Golf! DJ Samantha Ronson. Secret location disclosed to those who join www.facebook.com/smirnoff
11 hours ago