| cast |
 |
|
|
|
| Bryce Dallas Howard | Bryce Dallas Howard as Gwen Stacy | James Cromwell | James Cromwell as Captain John Stacy |
| James Franco | James Franco as Harry Osborn | JK Simmons | JK Simmons as J. Jonah Jameson |
| Kirsten Dunst | Kirsten Dunst as Mary Jane Watson | Rosemary Harris | Rosemary Harris as Aunt May |
| Thomas Haden Church | Thomas Haden Church as Flint Marko/Sandman | Topher Grace | Topher Grace as Eddie Brock/Venom |
| Danny Elfman | Danny Elfman Composer | Sam Raimi | Sam Raimi Director |
| Dylan Baker | Dylan Baker as Dr. Curt Connors | Tobey Maguire | Tobey Maguire as Peter Parker/Spider-Man |
| Stan Lee | Stan Lee | |