| cast |
 |
|
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| Alexa Vega | Alexa Vega as Carmen Cortez | Antonio Banderas | Antonio Banderas as Gregorio Cortez |
| Danny Trejo | Danny Trejo as Uncle Machete | Daryl Sabara | Daryl Sabara as Juni Cortez |
| Jeremy Piven | Jeremy Piven as Danger "Time Keeper" D'Amo | Jessica Alba | Jessica Alba as Marissa Cortez Wilson |
| Joel McHale | Joel McHale as Wilbur Wilson | Mason Cook | Mason Cook as Cecil Wilson |
| Rowan Blanchard | Rowan Blanchard as Rebecca Wilson | Ricky Gervais | Ricky Gervais as Argonaut |