Film & TV List | Role | Media |
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| Extremely Loud & Incredibly Close (2011) | Thomas Schell | Movie |
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| Larry Crowne (2011) | Larry Crowne | Movie |
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| Toy Story 3 (2010) | Woody (voice) | Movie |
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| Angels & Demons (2009) | Robert Langdon | Movie |
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| The Great Buck Howard (2008) | Mr. Gable | Movie |
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| Charlie Wilson's War (2007) | Charlie Wilson | Movie |
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| The Da Vinci Code (2006) | Robert Langdon | Movie |
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| Cars (2006) | Woody Car (voice) | Movie |
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| Magnificent Desolation: Walking on the Moon 3D (2005) | Narrator (documentary short) (voice) | Movie |
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| The Polar Express (2004) | Hero Boy | Movie |
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| Elvis Has Left the Building (2004) | Mailbox Elvis | Movie |
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| The Terminal (2004) | Viktor Navorski | Movie |
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| The Ladykillers (2004) | Professor G.H. Dorr | Movie |
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| Freedom: A History of Us (2003) | Abraham Lincoln | TV Show |
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| Catch Me If You Can (2002) | Carl Hanratty | Movie |
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| Road to Perdition (2002) | Michael Sullivan | Movie |
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| Band of Brothers (2001) | British officer | TV Movie |
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| Scene by Scene (2001) | n/a | TV Show |
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| Cast Away (2000) | Chuck Noland | Movie |
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| The Green Mile (1999) | Paul Edgecomb | Movie |
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| Toy Story 2 (1999) | Woody (voice) | Movie |
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| You've Got Mail (1998) | Joe Fox | Movie |
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| Saving Private Ryan (1998) | Capt. John H. Miller | Movie |
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| From the Earth to the Moon (1998) | Jean-Luc Despont | TV Movie |
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| That Thing You Do! (1996) | Mr. White | Movie |
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| Toy Story (1995) | Woody (voice) | Movie |
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| Apollo 13 (1995) | Jim Lovell | Movie |
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| Forrest Gump (1994) | Forrest Gump | Movie |
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| Vault of Horror I (1994) | n/a | TV Movie |
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| Philadelphia (1993) | Andrew Beckett | Movie |
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| Fallen Angels (1993) | Trouble Boy #1 | TV Show |
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| Sleepless in Seattle (1993) | Sam Baldwin | Movie |
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| A League of Their Own (1992) | Jimmy Dugan | Movie |
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| Tales from the Crypt (1992) | Baxter | TV Show |
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| The Bonfire of the Vanities (1990) | Sherman McCoy | Movie |
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| Joe Versus the Volcano (1990) | Joe | Movie |
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| Turner & Hooch (1989) | Det. Scott Turner | Movie |
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| The 'Burbs (1989) | Ray Peterson | Movie |
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| Punchline (1988) | Steven Gold | Movie |
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| Big (1988) | Josh Baskin | Movie |
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| Dragnet (1987) | Det. Pep Streebek | Movie |
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| Every Time We Say Goodbye (1986) | David Bradley | Movie |
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| Nothing in Common (1986) | David Basner | Movie |
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| The Money Pit (1986) | Walter Fielding, Jr. | Movie |
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| Volunteers (1985) | Lawrence Whatley Bourne III | Movie |
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| The Man with One Red Shoe (1985) | Richard Harlan Drew | Movie |
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| Bachelor Party (1984) | Rick Gassko | Movie |
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| Splash (1984) | Allen Bauer | Movie |
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| Family Ties (1983–1984) | Ned Donnelly | TV Show |
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| Mazes and Monsters (1982) | Robbie Wheeling | TV Movie |
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| Happy Days (1982) | Dr. Dwayne Twitchell | TV Show |
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| Taxi (1982) | Gordon | TV Show |
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| Bosom Buddies (1980–1982) | Kip Wilson | TV Show |
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| The Love Boat (1980) | Rick Martin | TV Show |
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| He Knows You're Alone (1980) | Elliot | Movie |
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